Voxel-wise TAC modeling in PKIN

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Voxel-wise TAC modeling in PKIN

After the transfer from the PVIEW tool the voxel-wise TACs are arranged in the Region list labeled with the VOI name followed by the voxel coordinate in the image. As for average TACs, the blood and plasma data have to be loaded, or a reference approach has to be used.


The whole PKIN functionality is then available for modeling. For instance, a few TACs can be averaged, a 1-tissue compartment model fitted as illustrated, propagated to all TACs using the Copy to All Regions entry Model & Par, and fitted with Fit model, all regions. Another possibility is to transfer the averaged TACs also from PVIEW, use them for setting up the proper model, propagate and fit.