Batch based on Model Definitions

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Batch based on Model Definitions

If .km files have been selected it is assumed that appropriate configurations are included for the following Operations:

Fit each individual region per file

All regional TACs are fitted with the respective models as defined in the .km file.

Perform one coupled fit per file

Performs coupled fitting with the model and coupling as defined in the .km file.

Perform a Monte Carlo simulation for the active region per file

Using the noise and model definitions in the file a Monte Carlo simulation of the current TAC is performed.

Perform a Monte Carlo simulation for each region

As above, but applied to all regional TACs. Can for instance be used to evaluate the sensitivity at different parameter combinations.

Perform one coupled Monte Carlo simulation per file

Monte Carlo simulation using the coupled fitting and Monte Carlo settings defined in the file.

Copy model parameters from KM to kinPar file

A convenience tool for aggregating the parameters of number of KM files into one tabular text file. Note that a Parameter Results file must be defined with the New file button, or the results can be appended to an existing file selected with the Append to file button.

Batch with Model Configuration Files

The batch mode also allows fitting multiple models to each data file. To do so, corresponding .kmModel files can be selected with the Add model button in the Kinetic .

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In this situation, only the Fit each individual region option is available. The results of the different model fits are saved in the regional model histories.

Fitting Options

The Model fit options give access to the mechanisms for improving objectivity and reliability of the results discussed in Fitting Options on Extras Panel with one exception. The First fit blood models option is intended for cases, where interpolation functions are defined for the different blood components but not yet fitted.